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BDBM27097 2-[(2R)-piperidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide::cyclic amine-containing benzimidazole carboxamide, 8a

SMILES: NC(=O)c1cccc2nc([nH]c12)[C@H]1CCCCN1

InChI Key: InChIKey=QRGBDUGNPYKQHW-SNVBAGLBSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27097   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27097
PNG
(2-[(2R)-piperidin-2-yl]-1H-1,3-benzodiazole-4-carb...)
Show SMILES NC(=O)c1cccc2nc([nH]c12)[C@H]1CCCCN1
Show InChI InChI=1S/C13H16N4O/c14-12(18)8-4-3-6-9-11(8)17-13(16-9)10-5-1-2-7-15-10/h3-4,6,10,15H,1-2,5,7H2,(H2,14,18)(H,16,17)/t10-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
37 -10.0n/an/an/an/an/a8.022



Abbott Laboratories



Assay Description
PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...


Bioorg Med Chem 16: 6965-75 (2008)


Article DOI: 10.1016/j.bmc.2008.05.044
BindingDB Entry DOI: 10.7270/Q2JD4V3X
More data for this
Ligand-Target Pair