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BDBM270999 US10071086, Compound 373

SMILES: CC(C)(C)C(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3ccoc3)c2c1

InChI Key: InChIKey=JGZZWWGXSKYNLV-ZNTNEXAZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270999   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM270999
PNG
(US10071086, Compound 373)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C26H20N8O2/c1-26(2,3)25(35)30-17-6-15(8-27-10-17)16-7-18-22(33-34-23(18)29-9-16)24-31-20-12-28-11-19(21(20)32-24)14-4-5-36-13-14/h4-13H,1-3H3,(H,30,35)/b24-22+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 70n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair