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BDBM27151 2-(1-cyclobutyl-2-methylpyrrolidin-2-yl)-1H-1,3-benzodiazole-4-carboxamide::benzimidazole carboxamide, 16

SMILES: CC1(CCCN1C1CCC1)c1nc2cccc(C(N)=O)c2[nH]1

InChI Key: InChIKey=IGZLGFQFXDRWON-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM27151
PNG
(2-(1-cyclobutyl-2-methylpyrrolidin-2-yl)-1H-1,3-be...)
Show SMILES CC1(CCCN1C1CCC1)c1nc2cccc(C(N)=O)c2[nH]1
Show InChI InChI=1S/C17H22N4O/c1-17(9-4-10-21(17)11-5-2-6-11)16-19-13-8-3-7-12(15(18)22)14(13)20-16/h3,7-8,11H,2,4-6,9-10H2,1H3,(H2,18,22)(H,19,20)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
31 -10.1n/an/an/an/an/a8.022



Abbott Laboratories



Assay Description
PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...


J Med Chem 52: 514-23 (2009)


Article DOI: 10.1021/jm801171j
BindingDB Entry DOI: 10.7270/Q2DN43CK
More data for this
Ligand-Target Pair