BDBM271545 US10065941, Compound I-046::US9732060, Compound I-046

SMILES COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ncccc3C#N)cc2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key InChIKey=KHGVWZBOVSZOOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271545   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM271545(US10065941, Compound I-046 | US9732060, Compound I...)
Affinity DataIC50:  19nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM271545(US10065941, Compound I-046 | US9732060, Compound I...)
Affinity DataIC50:  19nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent