BDBM2725 3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)cyclopropyl]-1-(5-cyanopyridin-2-yl)urea::N-[cis-2-(2-Chloro-3-ethoxy-6-fluorophenyl)cyclopropyl]-N-[2-(5-cyanopyridyl)]urea::urea-PETT deriv. 10
SMILES CCOc1ccc(F)c(C2CC2NC(=O)Nc2ccc(cn2)C#N)c1Cl
InChI Key InChIKey=CBDHDNQKYMVBTK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2725
Affinity DataIC50: 4.30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Medivir
Medivir
Affinity DataIC50: 183nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Medivir
Medivir
Affinity DataIC50: 130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair