BDBM2725 3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)cyclopropyl]-1-(5-cyanopyridin-2-yl)urea::N-[cis-2-(2-Chloro-3-ethoxy-6-fluorophenyl)cyclopropyl]-N-[2-(5-cyanopyridyl)]urea::urea-PETT deriv. 10

SMILES CCOc1ccc(F)c(C2CC2NC(=O)Nc2ccc(cn2)C#N)c1Cl

InChI Key InChIKey=CBDHDNQKYMVBTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2725   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2725(3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)cyclopropyl...)
Affinity DataIC50:  4.30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2725(3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)cyclopropyl...)
Affinity DataIC50:  183nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2725(3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)cyclopropyl...)
Affinity DataIC50:  130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed