BDBM2730 1-(5-cyanopyridin-2-yl)-3-[2-(3-acetyl-6-fluoro-2-hydroxyphenyl)cyclopropyl]urea::N-[cis-2-(3-Acetyl-6-fluoro-2-hydroxyphenyl)cyclopropyl]-N-[2-(5-cyanopyridyl)]urea::urea-PETT deriv. 15

SMILES CC(=O)c1ccc(F)c(C2CC2NC(=O)Nc2ccc(cn2)C#N)c1O

InChI Key InChIKey=MNZXPIGNPIOMFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2730   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2730(1-(5-cyanopyridin-2-yl)-3-[2-(3-acetyl-6-fluoro-2-...)
Affinity DataIC50:  5.30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2730(1-(5-cyanopyridin-2-yl)-3-[2-(3-acetyl-6-fluoro-2-...)
Affinity DataIC50:  98nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2730(1-(5-cyanopyridin-2-yl)-3-[2-(3-acetyl-6-fluoro-2-...)
Affinity DataIC50:  16nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed