BDBM273014 (R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-N-(1-phenylcyclopropyl)pyrrolidine-1-carboxamide::US10065972, Example 12
SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)NC1(CC1)c1ccccc1
InChI Key InChIKey=XMNXMZFUDQMJCZ-OAHLLOKOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273014
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 130nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair