BDBM273053 2-[(R)-1-(2-phenoxyacetyl)pyrrolidin-2-yl]-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one::US10065972, Example 145

SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)COc1ccccc1

InChI Key InChIKey=UKIFNBKNUVIGHN-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273053   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273053(2-[(R)-1-(2-phenoxyacetyl)pyrrolidin-2-yl]-7-(prop...)
Affinity DataIC50:  1.50E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent