BDBM273084 (R)-N-benzyl-1-(6-cyclopentyl-7-oxo-6,7-dihydro-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 238

SMILES O=C(NCc1ccccc1)[C@H]1CCCN1c1nc2c(ncn(C3CCCC3)c2=O)s1

InChI Key InChIKey=KHZUIXRRCCNRHG-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273084   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273084((R)-N-benzyl-1-(6-cyclopentyl-7-oxo-6,7-dihydro-[1...)
Affinity DataIC50:  16nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent