BDBM273155 (R)-N-benzyl-1-[(R)-6,8-dimethyl-10-oxo-5,7,8,10-tetrahydro-6H-pyrazino[1,2-a][1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide::US10065972, Example 601

SMILES C[C@@H]1CN(C)Cc2nc3sc(nc3c(=O)n12)N1CCC[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=WZGCZNFDGXOSMZ-GDBMZVCRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273155   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273155((R)-N-benzyl-1-[(R)-6,8-dimethyl-10-oxo-5,7,8,10-t...)
Affinity DataIC50:  140nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent