BDBM273155 (R)-N-benzyl-1-[(R)-6,8-dimethyl-10-oxo-5,7,8,10-tetrahydro-6H-pyrazino[1,2-a][1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide::US10065972, Example 601
SMILES C[C@@H]1CN(C)Cc2nc3sc(nc3c(=O)n12)N1CCC[C@@H]1C(=O)NCc1ccccc1
InChI Key InChIKey=WZGCZNFDGXOSMZ-GDBMZVCRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273155
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 140nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair