BDBM273197 (R)-N-benzyl-1-[2-(1-chlorocyclopropyl)-4-oxo-3,4-dihydropyrido[3,2-d]pyrimidin-6-yl]pyrrolidine-2-carboxamide::US10065972, Example 711

SMILES ClC1(CC1)c1nc2ccc(nc2c(=O)[nH]1)N1CCC[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=VGQKBYQLONGFKU-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273197   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273197((R)-N-benzyl-1-[2-(1-chlorocyclopropyl)-4-oxo-3,4-...)
Affinity DataIC50:  190nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent