BDBM273214 US10065973, Example 10-A::US10065973, Example 10-B

SMILES [H][C@]1(C[C@@]([H])([C@@H](C)O)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O)[C@@H](O)CC.[H][C@]1(C[C@@]([H])([C@H](C)O)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O)[C@@H](O)CC

InChI Key InChIKey=CORKCUXYPMWPRW-UEVLEYMYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 273214   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM273214(US10065973, Example 10-A | US10065973, Example 10-...)
Affinity DataEC50:  3.50E+4nMAssay Description:HEK293-Blue-hTLR7 cells were incubated at a density of 250,000-450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Modif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM273214(US10065973, Example 10-A | US10065973, Example 10-...)
Affinity DataEC50:  2.70E+3nMAssay Description:HEK293-Blue-hTLR7 cells were incubated at a density of 250,000-450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Modif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent