BDBM274428 US95556117, Example 92,4-Fluoro-7-methoxy-1H-indole-5-carboxylic acid (1-hydroxy-cyclohexylmethyl)-amide

SMILES COc1cc(C(=O)NCC2(O)CCCCC2)c(F)c2cc[nH]c12

InChI Key InChIKey=YQTAKJFHWIWIOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274428   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM274428(US95556117, Example 92,4-Fluoro-7-methoxy-1H-indol...)
Affinity DataIC50:  45nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent