BDBM274510 US9556179, Compound 80::oxetan-3-yl 4-(5-(2-(2- fluoroisonicotinamido)imidazo[1,2- b]pyridazin-6-yl)-4-(4-fluorophenyl)- 1H-imidazol-1-yl)piperidine-1- carboxylate

SMILES Fc1ccc(cc1)-c1ncn(C2CCN(CC2)C(=O)OC2COC2)c1-c1ccc2nc(NC(=O)c3ccnc(F)c3)cn2n1

InChI Key InChIKey=YJNVHDXGHUWUIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274510   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274510(US9556179, Compound 80 | oxetan-3-yl 4-(5-(2-(2- f...)
Affinity DataIC50:  0.171nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274510(US9556179, Compound 80 | oxetan-3-yl 4-(5-(2-(2- f...)
Affinity DataIC50:  0.809nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent