BDBM274530 N-(6-(1-(1-(2-amino-2- oxoethyl)piperidin-4-yl)-4-(4- fluorophenyl)-1H-imidazol-5- yl)imidazo[1,2-b] pyridazin-2-yl)-4- methyl-2-(pyridin-3-yl) thiazole-5- carboxamide::US9556179, Compound 100

SMILES Cc1nc(sc1C(=O)Nc1cn2nc(ccc2n1)-c1c(ncn1C1CCN(CC(N)=O)CC1)-c1ccc(F)cc1)-c1cccnc1

InChI Key InChIKey=MEXRXSBQLFBVBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274530   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274530(N-(6-(1-(1-(2-amino-2- oxoethyl)piperidin-4-yl)-4-...)
Affinity DataIC50:  0.0910nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274530(N-(6-(1-(1-(2-amino-2- oxoethyl)piperidin-4-yl)-4-...)
Affinity DataIC50:  0.128nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent