BDBM27460 2-amino-5-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)-N-methylbenzamide::Amino-substituted diarylbenzamide, 8a

SMILES CNC(=O)c1cc(cc(c1N)-c1ccc(cc1)S(C)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=PEAZARIFDFJHCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27460   

LigandPNGBDBM27460(2-amino-5-(4-fluorophenyl)-3-(4-methanesulfonylphe...)
Affinity DataIC50: >1.58E+4nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27460(2-amino-5-(4-fluorophenyl)-3-(4-methanesulfonylphe...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27460(2-amino-5-(4-fluorophenyl)-3-(4-methanesulfonylphe...)
Affinity DataIC50: >1.58E+4nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed