BDBM27473 2-amino-5-phenyl-3-[4-(sulfamoylmethyl)phenyl]benzamide::Amino-substituted diarylbenzamide, 8n

SMILES NC(=O)c1cc(cc(c1N)-c1ccc(CS(N)(=O)=O)cc1)-c1ccccc1

InChI Key InChIKey=SNZXBPCCTHLEJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 27473   

LigandPNGBDBM27473(2-amino-5-phenyl-3-[4-(sulfamoylmethyl)phenyl]benz...)
Affinity DataIC50:  7.94E+3nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27473(2-amino-5-phenyl-3-[4-(sulfamoylmethyl)phenyl]benz...)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM27473(2-amino-5-phenyl-3-[4-(sulfamoylmethyl)phenyl]benz...)
Affinity DataIC50: >1.58E+4nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27473(2-amino-5-phenyl-3-[4-(sulfamoylmethyl)phenyl]benz...)
Affinity DataIC50:  3.98E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed