BDBM274982 (R/S)-N2-(tert-butyl)-N8-(2-hydroxy-1-(6- (trifluoromethyl)pyridin-3-yl)ethyl)-5-(3- (trifluoromethyl)phenyl)-3,4- dihydroisoquinoline-2,8(1H)-dicarboxamide (mixture of 2 enantiomers)::US9877957, Example 21
SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(ccc2-c1cccc(c1)C(F)(F)F)C(=O)N[C@@H](CO)c1ccc(nc1)C(F)(F)F
InChI Key InChIKey=HGCPDRMRZCIXFF-DEOSSOPVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 274982
Affinity DataIC50: 214nMpH: 7.0 T: 2°CAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair