BDBM274986 N2-(tert-butyl)-N8-(2-(2-methylimidazo[2,1- b][1,3,4]thiadiazol-6-yl)ethyl)-5-(3- (trifluoromethyl)phenyl)-3,4- dihydroisoquinoline-2,8(1H)-dicarboxamide::US9877957, Example 25
SMILES Cc1nn2cc(CCNC(=O)c3ccc(-c4cccc(c4)C(F)(F)F)c4CCN(Cc34)C(=O)NC(C)(C)C)nc2s1
InChI Key InChIKey=HCBRMZOYIAUILB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 274986
Affinity DataIC50: 271nMpH: 7.0 T: 2°CAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair