BDBM27503 5-AIQ::5-amino-1,2-dihydroisoquinolin-1-one::5-aminoisoquinolin-1(2H)-one::CHEMBL446240
SMILES Nc1cccc2c1cc[nH]c2=O
InChI Key InChIKey=SVASVGVAQIVSEZ-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 27503
Affinity DataIC50: 250nMAssay Description:Inhibition of calf thymus PARP-1More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PARP-1 (unknown origin) in broken nuclear preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human PARP-1 assessed as synthesis of [3H]-ADP-ribose polymers from [3H]-NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant PARP1 by Trevigen colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of calf thymus PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human PARP-1 after 10 mins by FlashPlate scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of full length human PARP-1 after 10 mins by FlashPlate scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair