BDBM275140 1-[(3R,4S) or (3S, 4R)-1- methyl-4-(2- methylphenyl)pyrrolidin-3- yl]-3-[1-(2-methylpyridin-4- yl)-1H-pyrazolo[3,4- c]pyridin-5-yl)urea::US9884048, Example 180::US9884048, Example 36

SMILES CN1C[C@H](NC(=O)Nc2cc3cnn(-c4ccnc(C)c4)c3cn2)[C@H](C1)c1ccccc1C

InChI Key InChIKey=PIKZAOBNOWWJRU-YADHBBJMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275140   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275140(1-[(3R,4S) or (3S, 4R)-1- methyl-4-(2- methylpheny...)
Affinity DataIC50:  0.280nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275140(1-[(3R,4S) or (3S, 4R)-1- methyl-4-(2- methylpheny...)
Affinity DataIC50:  0.830nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent