BDBM275145 1-(3-chlorobenzyl)-3-(1- pyridin-4-yl-1H- pyrazolo[3,4-c]pyridin-5- yl)urea::US9884048, Example 41

SMILES Clc1cccc(CNC(=O)Nc2cc3cnn(-c4ccncc4)c3cn2)c1

InChI Key InChIKey=SHMNWFVLBGCRIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275145   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275145(1-(3-chlorobenzyl)-3-(1- pyridin-4-yl-1H- pyrazolo...)
Affinity DataIC50:  0.5nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent