BDBM275375 1-cyclopentyl-7H-pyrrolo[3,2-::US9556187, Example 68

SMILES C1CCC(C1)c1nnn2cnc3[nH]ccc3c12

InChI Key InChIKey=QIGJFJBZCHRODG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 275375   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical Industries

US Patent
LigandPNGBDBM275375(1-cyclopentyl-7H-pyrrolo[3,2- | US9556187, Example...)
Affinity DataIC50:  500nMT: 2°CAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical Industries

US Patent
LigandPNGBDBM275375(1-cyclopentyl-7H-pyrrolo[3,2- | US9556187, Example...)
Affinity DataIC50:  9.10E+3nMT: 2°CAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical Industries

US Patent
LigandPNGBDBM275375(1-cyclopentyl-7H-pyrrolo[3,2- | US9556187, Example...)
Affinity DataIC50:  2.40E+3nMT: 2°CAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent