BDBM275417 1-[1-(4-fluorophenyl)-1H-pyrazolo[3,4- c]pyridin-5-yl]-3-[(1S)-2-hydroxy-2- methyl-1-phenylpropyl]urea::US9884048, Example 296

SMILES CC(C)(O)[C@@H](NC(=O)Nc1cc2cnn(-c3ccc(F)cc3)c2cn1)c1ccccc1

InChI Key InChIKey=CNYKTKDNRCZJOS-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275417   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275417(1-[1-(4-fluorophenyl)-1H-pyrazolo[3,4- c]pyridin-5...)
Affinity DataIC50:  0.810nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent