BDBM275418 (S)-1-(2-hydroxy-1-phenylpropyl)-3-(1-(2-methylpyridin-4-yl)-1H-pyrazolo[3,4-c]pyridin-5-yl)urea::US9884048, Example 297

SMILES CC(O)[C@@H](NC(=O)Nc1cc2cnn(-c3ccnc(C)c3)c2cn1)c1ccccc1

InChI Key InChIKey=WDSKHBKJGBRLEC-MZVUKIKXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275418   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275418((S)-1-(2-hydroxy-1-phenylpropyl)-3-(1-(2-methylpyr...)
Affinity DataIC50:  1.06nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent