BDBM275473 US9879013, 8(14)

SMILES Nc1ncnc2n(CC3CCN(CC3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=OODFMLQWPHKOIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 275473   

TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  2.20E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  1.77E+6nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  2.50E+6nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent