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BDBM275666 US10071086, Compound 581

SMILES: Fc1ccc(cc1)-c1cccc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1

InChI Key: InChIKey=DZSGBFYBLDUNNY-IMVLJIQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275666   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM275666
PNG
(US10071086, Compound 581)
Show SMILES Fc1ccc(cc1)-c1cccc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H18FN7O/c29-19-8-6-15(7-9-19)21-2-1-3-23-24(21)34-27(33-23)25-22-11-18(13-31-26(22)36-35-25)17-10-20(14-30-12-17)32-28(37)16-4-5-16/h1-3,6-14,16H,4-5H2,(H,32,37)/b27-25+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 48n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair