BDBM27571 5-[(3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicarbonitrile::Indazole Derivative, 1

SMILES Cc1n[nH]c2cccc(Oc3cc(cc(c3)C#N)C#N)c12

InChI Key InChIKey=BXHPUNFRXKKZLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27571   

TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27571(5-[(3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicar...)
Affinity DataIC50:  332nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed