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BDBM275738 US10071086, Compound 635

SMILES: Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cccc4[nH]3)-c3ccncc3)c2c1

InChI Key: InChIKey=MEPKKMAYPXODJA-XTQSDGFTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275738   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM275738
PNG
(US10071086, Compound 635)
Show SMILES Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cccc4[nH]3)-c3ccncc3)c2c1
Show InChI InChI=1S/C23H14N8/c24-16-8-14(10-26-12-16)15-9-18-21(30-31-22(18)27-11-15)23-28-19-3-1-2-17(20(19)29-23)13-4-6-25-7-5-13/h1-12H,24H2/b23-21+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 34n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair