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BDBM275757 US10071086, Compound 785

SMILES: CCC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cccc4[nH]3)-c3ccsc3)c2c1

InChI Key: InChIKey=NCQSAURFOJZBAU-WJTDDFOZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275757   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM275757
PNG
(US10071086, Compound 785)
Show SMILES CCC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cccc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C25H17N7OS/c1-2-21(33)28-17-8-15(10-26-12-17)16-9-19-23(31-32-24(19)27-11-16)25-29-20-5-3-4-18(22(20)30-25)14-6-7-34-13-14/h3-13H,2H2,1H3,(H,28,33)/b25-23+
PDB

GoogleScholar
AffyNet 
UniChem
n/an/a 10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair