BDBM275842 5-chloro-N-(N,N- dimethylsulfamoyl)-2- fluoro-4-(4-(methyl- sulfonyl)phenoxy) benzamide::US10071957, Example 61

SMILES CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(Oc2ccc(cc2)S(C)(=O)=O)cc1F

InChI Key InChIKey=TZUISDXTLMEBHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275842   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM275842(5-chloro-N-(N,N- dimethylsulfamoyl)-2- fluoro-4-(4...)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent