BDBM275863 US10071957, Example 82
SMILES CC(C)Oc1ncc(OCc2cc(F)c(cc2Cl)C(=O)NS(=O)(=O)N2CCC2)cc1Cl
InChI Key InChIKey=RNNXHRFXUSTNMQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 275863
Affinity DataIC50: 43nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair