BDBM275904 US10071974, Example 15::US10577336, Example 15

SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1CNCCO1

InChI Key InChIKey=MTNKGBAOBUNAEG-AWEZNQCLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275904   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275904(US10071974, Example 15 | US10577336, Example 15)
Affinity DataEC50:  244nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275904(US10071974, Example 15 | US10577336, Example 15)
Affinity DataEC50:  244nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent