BDBM276001 US10071974, Example 112::US10071974, Example 113::US10577336, Example 113

SMILES CC(C)CC(C)(NC(=O)[C@@H]1CNCCO1)c1ncc2c(C)cccn12

InChI Key InChIKey=ORFFERULYZTZIL-UCFFOFKASA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276001   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM276001(US10071974, Example 112 | US10071974, Example 113 ...)
Affinity DataEC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM276001(US10071974, Example 112 | US10071974, Example 113 ...)
Affinity DataEC50:  380nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM276001(US10071974, Example 112 | US10071974, Example 113 ...)
Affinity DataEC50:  5.50E+3nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM276001(US10071974, Example 112 | US10071974, Example 113 ...)
Affinity DataEC50:  380nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent