BDBM276064 2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]imidazol-44-yl]-4-(1H-triazol-4-yl)pyridine::US10071984, Example 26::US10174003, Example 26::US9896436, Example 26
SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
InChI Key InChIKey=NZTCCZUHIHSENS-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 276064
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: >500nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair