BDBM27641 1-(3-{[(2S)-2-aminopropanamido]methyl}phenyl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole scaffold, 1b
SMILES COc1ccccc1CNC(=O)c1cc(nn1-c1cccc(CNC(=O)[C@H](C)N)c1)C(F)(F)F
InChI Key InChIKey=KZCJXNWWNKSCHI-AWEZNQCLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 27641
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant CARM1 expressed in Sf9 cells by microbeta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 9.0 T: 2°CAssay Description:Histone H3 is used as the substrate for CARM-1 enzyme, and the methylation is monitored using tritiated S-Adenosyl-Methionine (SAM) as a methyl donor...More data for this Ligand-Target Pair