BDBM27684 2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxamide::CHEMBL131820::benzimidazole carboxamide, 2

SMILES COc1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O

InChI Key InChIKey=MKRGNKRNZLHINT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 27684   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataKi:  6.80nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))TBA
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  3.22E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  1.16E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))TBA
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  9.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  60nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP-1 enzyme assay was carried out in reaction mixture consisting of Escherichia coli str...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  980nMMore data for this Ligand-Target Pair
In DepthDetails