BDBM27709 2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-yl]propyl}-8-methyl-3,4-dihydroquinazolin-4-one::CHEMBL401843::quinazolinone analogue, 1e
SMILES Cc1cccc2c1nc(CCCN1CCC(=CC1)c1ccc(F)cc1)[nH]c2=O
InChI Key InChIKey=LOFDUAJQRUYHBR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27709
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 167nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair