BDBM277094 4-(2-fluoro-4- methylphenyl)-7-{[1-(1- methylethyl)-1H-pyrazol- 5-yl]methyl}-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-12

SMILES CC(C)n1nccc1CN1CCc2c(C1)nc(cc2-c1ccc(C)cc1F)C(N)=O

InChI Key InChIKey=OWZZMUHEMNVUND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277094   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277094(4-(2-fluoro-4- methylphenyl)-7-{[1-(1- methylethyl...)
Affinity DataIC50:  9.90E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent