BDBM277097 (S) or (R)-4-(2,4- difluorophenyl)-8- methyl-7-{[1-(1- methylethyl)-1H-pyrazol- 5-yl]methyl}-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-15A::US10072003, Example 1-15B

SMILES CC(C)n1nccc1CN1CCc2c(nc(cc2-c2ccc(F)cc2F)C(N)=O)C1C

InChI Key InChIKey=FXWSMLLCYKSBBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 277097   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277097((S) or (R)-4-(2,4- difluorophenyl)-8- methyl-7-{[1...)
Affinity DataIC50:  5.30E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277097((S) or (R)-4-(2,4- difluorophenyl)-8- methyl-7-{[1...)
Affinity DataIC50:  5.80E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent