BDBM277102 (S) or (R)-8-methyl-7- {[1-(1-methylethyl)-1H- pyrazol-5-yl]methyl}-4- piperidin-1-yl-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-19

SMILES CC(C)n1nccc1CN1CCc2c(cc(nc2C1C)C(N)=O)N1CCCCC1

InChI Key InChIKey=RXCSWMPSKALJOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277102   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277102((S) or (R)-8-methyl-7- {[1-(1-methylethyl)-1H- pyr...)
Affinity DataIC50:  1.32E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent