BDBM277130 4-(2,4-difluorophenyl)-7-{[6- (trifluoromethyl)pyrimidin-4-yl]methyl}- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-23

SMILES NC(=O)c1cc(c2CCN(Cc3cc(ncn3)C(F)(F)F)Cc2n1)-c1ccc(F)cc1F

InChI Key InChIKey=QAMZKRBHXOGNOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277130   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277130(4-(2,4-difluorophenyl)-7-{[6- (trifluoromethyl)pyr...)
Affinity DataIC50:  5.70E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent