BDBM277131 4-(3-cyclopropylisothiazol-5-yl)-7-[(2- cyclopropylpyridin-4-yl)methyl]-5,6,7,8- tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-24

SMILES NC(=O)c1cc(-c2cc(ns2)C2CC2)c2CCN(Cc3ccnc(c3)C3CC3)Cc2n1

InChI Key InChIKey=ZXEQAXYMOLZHBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277131   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277131(4-(3-cyclopropylisothiazol-5-yl)-7-[(2- cyclopropy...)
Affinity DataIC50:  1.82E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent