BDBM277152 4-(4-methoxy-1H-pyrazol- 1-yl)-7-{[2- (trifluoromethyl)pyridin-4- yl]methyl}-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 5-8

SMILES COc1cnn(c1)-c1cc(nc2CN(Cc3ccnc(c3)C(F)(F)F)CCc12)C(N)=O

InChI Key InChIKey=PXWHMYKEYYISGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277152   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277152(4-(4-methoxy-1H-pyrazol- 1-yl)-7-{[2- (trifluorome...)
Affinity DataIC50:  8.87E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent