BDBM277166 US10072003, Example 8-2A::US10072003, Example 8-2B

SMILES NC(=O)c1cc(c2CCN(Cc2n1)C(CO)c1ccccc1)-c1ccc(F)cc1F

InChI Key InChIKey=WMUFETNWXKXODX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 277166   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277166(US10072003, Example 8-2A | US10072003, Example 8-2...)
Affinity DataIC50:  1.15E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277166(US10072003, Example 8-2A | US10072003, Example 8-2...)
Affinity DataIC50:  9.90E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent