BDBM277172 4-(4-chloro-2-fluorophenyl)-7-[(2- methoxypyrimidin-4-yl)methyl]-5,6,7,8- tetrahydro-1,7-naphthyridine-2-carboxamide::US10072003, Example 9-3

SMILES COc1nccc(CN2CCc3c(C2)nc(cc3-c2ccc(Cl)cc2F)C(N)=O)n1

InChI Key InChIKey=XCHIPSIWFHMMSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277172   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277172(4-(4-chloro-2-fluorophenyl)-7-[(2- methoxypyrimidi...)
Affinity DataIC50:  1.42E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent