BDBM277693 2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl) ureido)-naphthalen-1-yl)oxy)pyridin-2-yl)amino)-5-methoxyphenoxy)ethoxy)ethyl)thio)acetic acid::US10072034, Example 19

SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCSCC(O)=O)c1

InChI Key InChIKey=DPGHJZKWVBDEMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277693   

TargetInterleukin-8(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Affinity DataIC50:  2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent