BDBM27828 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 11::4-fluoro-2-{[2-({2-methoxy-4-[4-(propan-2-yl)piperazin-1-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide::CHEMBL459069

SMILES COc1cc(ccc1Nc1nc(Nc2cc(F)ccc2C(N)=O)c2cc[nH]c2n1)N1CCN(CC1)C(C)C

InChI Key InChIKey=NSJFKRFDKHDDIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27828   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27828(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 11 | ...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27828(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 11 | ...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed