BDBM278759 N-(2-bromophenyl)-2- (1,4-diazepan-1- yl)pyrrolo[1,2- b]pyridazine-7- carboxamide trifluoroacetate::US10040798, Example 57

SMILES OC(=O)C(F)(F)F.Brc1ccccc1NC(=O)c1ccc2ccc(nn12)N1CCCNCC1

InChI Key InChIKey=WDGNVONDNMMEEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 278759   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM278759(N-(2-bromophenyl)-2- (1,4-diazepan-1- yl)pyrrolo[1...)
Affinity DataIC50:  3.96E+3nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent