BDBM278779 2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-(2-bromothiophen- 3-yl)pyrrolo[1,2- b]pyridazine-7- carboxamide trifluoroacetate::US10040798, Example 77
SMILES OC(=O)C(F)(F)F.N[C@H]1CCCC[C@H]1Nc1ccc2ccc(C(=O)Nc3ccsc3Br)n2n1
InChI Key InChIKey=CSKDBHJMHCVZHV-JHEYCYPBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278779
Affinity DataIC50: 11nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair